EPISODE 370: The Neuroscience of Addiction

You don’t manage to leave the office until 8 pm. Traffic is terrible, so it takes you an hour to get home. One of your relatives is sick and has been texting you all day, but you haven’t had a moment to call to check in. Your taxes are due in a few weeks, and you don’t have any idea how much you’ll owe. You’re best friend is just not there for you the way she used to be. She hasn’t called you in weeks.

It’s Thursday evening, and you’re all alone in your kitchen trying to manage this very common mundane overwhelm that comes with everyday life. So what do you do?

No one is looking, no one will ask… Is it a Haagen Dazs and Netflix binge? Sleeping pills and a glass of red wine? Do you vape or watch porn? We all have our escapes. When the pressure cooker of our lives builds, it has to find a release. But most of our choices are destructive. On this week’s show, we’ll talk about how to find a better way.

What You’ll Learn:

  • Why sobriety is often a sliding scale
  • How dose and frequency often determine damage and risk
  • How cocaine was not deemed addictive until 1986
  • Why the opposite of addiction is choice
  • The challenges of positive escapes in a stressful world


Grisel is a behavioral neuroscientist with expertise in pharmacology and genetics whose research focuses on determining root causes of drug addiction. She’s the author of a new book, Never Enough: The Neuroscience and Experience of Addiction.

Nutritional Tip of the Week:

  • Pink Salmon

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